Accurate

Octopus achieves class-leading accuracy in short-read small variant calling, including for germline and somatic mutations using a combination of Bayesian modelling and machine learning.

Versatile

Designed to work with sequencing data generated from different experimental setups, Octopus can call variants in germline, bulk tumour, metagenomic, and single-cell datasets.

Easy to use

Common read pre-processing steps are handled internally. A uniform interface simplifies workflows. Multithreading is built-in. Octopus is designed with the user in mind.